Medsyndesign is a medicinal chemistry consultancy providing high quality compound design to pre-clinical drug discovery projects. A range of chemistry inputs are provided using our 25 years of experience in multidisciplinary projects in Pharma R&D. Working in a collaborative and confidential way we adopt a flexible approach to improve each client’s project drug delivery.

Hit Identification (HI): We will evaluate results from your hit generation campaign to select the best quality starting point.
Lead Optimization (LO): Having delivered the medicinal chemistry strategy in many successful LO programmes, we will bring our modern industrial expertise to guide your discovery projects through the LO phase.
Candidate Drug (CD): Our broad interdisciplinary knowledge will maximize the impact of medicinal chemistry design to solve the problems and issues encountered during CD selection.

Services
• One-off Consultancy
• Longer Term Project Involvement and Input
• Intellectual Property Landscape Evaluation
• Independent Project Review and Critique
• Advice on Selection and Use of CROs
• Lectures and Short Courses in Medicinal Chemistry

Expertise
• Small Molecule and Peptide Drug Design
• Oral and Inhaled Delivered Drug Projects
• Structure Based Drug Design
• Physical Property Optimization
• Hit and Lead Series Analysis and Follow-up
• Synthetic Route Design for Analogue Series